in an extremely serious or desperate way

• with urgent, acute severity
• to a very great and alarming degree

以极其严重或绝望的方式

• 带有紧迫而严峻的程度
• 达到非常高且令人担忧的程度

severely or grievously, causing serious harm

• in a way that affects conditions very badly
• with harsh, ruinous impact

严重地；造成重大伤害

• 使状况大幅恶化的方式
• 具有严酷、毁灭性的影响