Crazy; insane; out of one’s mind.

• Of livestock: made erratic by eating locoweed.

Informal abbreviation of locomotive.

• A railroad engine in rail jargon.

Musical direction: return to written pitch.

• Cancels 8va or 8vb octave transposition.

A locoweed plant (Astragalus or Oxytropis).

• Causes locoism in grazing animals.

To poison with the locoweed plant.

• To render insane, especially livestock.