A power or principle thought to predetermine events

• The inevitable outcome or destiny of a person or thing
• Often implies doom, ruin, or unavoidable misfortune

Fate personified as a controlling force

• Often the Fates, the deities who allot destiny

The ultimate behavior and disposition of a chemical in the environment

• Includes transport, transformation, and final sinks

The mature identity and role a cell or tissue will adopt

• The developmental outcome predetermined by lineage and signals

To determine or fix the outcome in advance

• To doom or destine